AI in neurology: stroke AI detects 62% of large-vessel occlusions versus up to 96% for human readers

Zenodo 2026 · 1 min read
Sensitivity · AI for large-vessel occlusion
0.62
Versus 0.65–0.96 for eight human readers, 500 patients (Slater et al., 2024)
AUROC · multimodal dementia AI
0.94
Cognitive-status classification, 51,269 participants (Xue et al., 2024)
Sources in the corpus
27

Arkangel AI whitepaper: a 27-source review maps neurology AI from stroke imaging to dementia and finds little proof of prospective benefit or regional performance.

This whitepaper examines selected AI applications in neurology: stroke imaging and workflow, EEG and epilepsy, multimodal dementia assessment, movement analysis, multiple sclerosis follow-up and document synthesis with large language models. It is a narrative synthesis of 27 sources with a main clinical cutoff of June 15, 2026, organized by clinical task and by maturity stage, from retrospective development to routine implementation. It is non-peer-reviewed gray literature published by Arkangel AI, and the evidence it cites does not validate any Arkangel product.

Stroke imaging has the most developed operational pathway in the corpus, but performance is uneven: in a comparison on scans from 500 patients, one commercial tool detected large-vessel occlusions with a sensitivity of 0.62, against 0.65–0.96 for eight human readers, which the authors note is insufficient to rule out an occlusion. A multimodal dementia model trained on 51,269 participants reached a microaveraged AUROC of 0.94 for cognitive status and 0.96 for etiologies, without established prospective effects on care. For EEG, dementia and other domains, support for review and data integration is better established than replacement of specialist judgment, and the regional sources found document stroke-care inequalities without demonstrating neurological-AI performance in Latin America.

Results at a glance

The headline numbers from the paper, in plain language.

How the model performed

Higher is better

Data: Versus 0.65–0.96 for eight human readers, 500 patients (Slater et al., 2024) · Cognitive-status classification, 51,269 participants (Xue et al., 2024) — Zenodo 2026

Scores reported on a 0–1 scale (AUC, kappa) are drawn ×100.

Show the numbers as a table
MetricValueWhat it means
Sensitivity · AI for large-vessel occlusion0.62Versus 0.65–0.96 for eight human readers, 500 patients (Slater et al., 2024)
AUROC · multimodal dementia AI0.94Cognitive-status classification, 51,269 participants (Xue et al., 2024)
Sources in the corpus27

How to cite

Katherine Monsalve, Natalia Castaño-Villegas, Jose Zea, Laura Velásquez. AI in Neurology Selected Applications, Evidence Maturity, and Governance for Latin America. Zenodo. 2026. https://doi.org/10.5281/zenodo.23092130

@article{monsalve2026neurology,
  title     = {{AI in Neurology Selected Applications, Evidence Maturity, and Governance for Latin America}},
  author    = {Katherine Monsalve and Natalia Castaño-Villegas and Jose Zea and Laura Velásquez},
  journal   = {Zenodo},
  year      = {2026},
  doi       = {10.5281/zenodo.23092130},
  url       = {https://doi.org/10.5281/zenodo.23092130}
}

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