AI in obstetrics and gynecology: cervical cytology AI reaches AUC 0.947, but regional evidence rests on two Mexican cohorts

Zenodo 2026 · 1 min read
AUC · AI cervical cytology grading
0.947
Prospective validation in 2,780 participants (Wang et al., 2024)
Latin American cohorts
2
Mexican preeclampsia and gestational diabetes models
References in the corpus
27

Arkangel AI whitepaper: a 27-reference review finds cervical screening and imaging AI most mature in OB-GYN, with no domain ready for routine use in Latin America.

This whitepaper reviews AI support for screening, imaging and prediction in gynecology and obstetrics, with a focus on Latin America. It is a narrative evidence synthesis built from PubMed searches run in June and July 2026, with a final corpus of 27 references, and it sorts each application into five maturity levels, from retrospective development to monitored routine implementation. It is non-peer-reviewed gray literature published by Arkangel AI, and it does not evaluate any Arkangel product.

Cervical screening and image analysis have the most mature evidence: one cervical cytology model reached an AUC of 0.947 in prospective validation with 2,780 participants, while a liquid-based cytology model showed lower specificity than cytopathologists (0.831 versus 0.901). Fetal ultrasound is an active area, and machine-learning models for preeclampsia and gestational diabetes are numerous but heterogeneous, with pooled AUROC of 0.8492 for gestational diabetes and substantial heterogeneity. Direct regional evidence comes from two Mexican cohorts, including a preeclampsia model with an AUC of 0.897 for preterm disease. The authors conclude that no domain yet supports a claim of safe routine implementation in Latin America and call for external validation, bias audits and process measures before claims of clinical impact.

Results at a glance

The headline numbers from the paper, in plain language.

MetricValueWhat it means
AUC · AI cervical cytology grading0.947Prospective validation in 2,780 participants (Wang et al., 2024)
Latin American cohorts2Mexican preeclampsia and gestational diabetes models
References in the corpus27

How to cite

Katherine Monsalve, Natalia Castaño-Villegas, Jose Zea, Laura Velásquez. Current State of AI Support for Screening, Imaging, and Prediction in Gynecology and Obstetrics Evidence, Limitations, and a Responsible Agenda for Latin America. Zenodo. 2026. https://doi.org/10.5281/zenodo.23087262

@article{monsalve2026current,
  title     = {{Current State of AI Support for Screening, Imaging, and Prediction in Gynecology and Obstetrics Evidence, Limitations, and a Responsible Agenda for Latin America}},
  author    = {Katherine Monsalve and Natalia Castaño-Villegas and Jose Zea and Laura Velásquez},
  journal   = {Zenodo},
  year      = {2026},
  doi       = {10.5281/zenodo.23087262},
  url       = {https://doi.org/10.5281/zenodo.23087262}
}

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