AI in surgery and anesthesiology: 8 randomized trials and no proven general benefit

Zenodo 2026 · 1 min read
Randomized-trial reports · hypotension AI
8
568 participants counted with overlap; no significant difference in hypotension burden
Sources synthesized
28
PubMed, WHO, FDA and PAHO; cutoff June 15, 2026
Countries in the LASOS perioperative cohort
17
22,126 patients; 14.6% with complications

Arkangel AI whitepaper: across 28 sources, hypotension alerts lead perioperative AI evidence, yet 8 trials show no clear general benefit.

This Arkangel AI whitepaper is a narrative evidence synthesis, not a peer-reviewed study or a systematic review, of what AI can and cannot do today in surgery and anesthesiology, with a focus on Latin America. It draws on 28 sources from a targeted PubMed search and official WHO, FDA and PAHO documents (cutoff June 15, 2026) and grades six domains, from intraoperative hypotension alerts and complication prediction to surgical video, skill assessment and operating-room scheduling, by evidence stage, from retrospective development to routine implementation.

The evidence closest to clinical use is intraoperative hypotension prediction: a meta-analysis of 8 randomized-trial reports (568 participants counted with overlap), 7 of them on the Hypotension Prediction Index, found no significant difference in hypotension burden once the largest trial was included (mean difference 0.22 mmHg, 95% CI −0.03 to 0.48; I² 93.8%). Regional studies, such as a Bogotá surgical-duration model with an RMSE of 26 minutes and the LASOS cohort of 22,126 patients in 17 countries with 14.6% complications, show research capacity but not clinical effectiveness. The authors conclude that AI can support bounded perioperative tasks under local validation and governance, not autonomous intraoperative decisions.

Results at a glance

The headline numbers from the paper, in plain language.

MetricValueWhat it means
Randomized-trial reports · hypotension AI8568 participants counted with overlap; no significant difference in hypotension burden
Sources synthesized28PubMed, WHO, FDA and PAHO; cutoff June 15, 2026
Countries in the LASOS perioperative cohort1722,126 patients; 14.6% with complications

How to cite

Katherine Monsalve, Natalia Castaño-Villegas, Jose Zea, Laura Velásquez. Current State of AI in Surgery and Anesthesiology Selected Applications, Limits, and a Responsible Agenda for Latin America. Zenodo. 2026. https://doi.org/10.5281/zenodo.23088752

@article{monsalve2026current,
  title     = {{Current State of AI in Surgery and Anesthesiology Selected Applications, Limits, and a Responsible Agenda for Latin America}},
  author    = {Katherine Monsalve and Natalia Castaño-Villegas and Jose Zea and Laura Velásquez},
  journal   = {Zenodo},
  year      = {2026},
  doi       = {10.5281/zenodo.23088752},
  url       = {https://doi.org/10.5281/zenodo.23088752}
}

More research from Arkangel AI

All research →

For hospitals and insurers

Validate these results at your institution

We run the model on your own clinical records with your team, under your privacy and governance rules.

Start a research partnership
Read paperCite